S100B antibody
CAT:
710-FNab07566
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
S100B antibody
- Background: Weakly binds calcium but binds zinc very tightly-distinct binding sites with different affinities exist for both ions on each monomer. Physiological concentrations of potassium ion antagonize the binding of both divalent cations, especially affecting high-affinity calcium-binding sites. Binds to and initiates the activation of STK38 by releasing autoinhibitory intramolecular interactions within the kinase. Interaction with AGER after myocardial infarction may play a role in myocyte apoptosis by activating ERK1/2 and p53/TP53 signaling. Could assist ATAD3A cytoplasmic processing, preventing aggregation and favoring mitochondrial localization. May mediate calcium-dependent regulation on many physiological processes by interacting with other proteins, such as TPR-containing proteins, and modulating their activity.
- Synonyms: Protein S100-B|S-100 protein beta chain|S-100 protein subunit beta|S100 calcium-binding protein B|S100B
- CAS Number: 9007-83-4
- Gene ID: 6285
- UniProt: P04271
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: S100 calcium binding protein B
- Target: S100B
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB, IHC, IF
- Field of Research: Cancer, Immunology, Signal Transduction
- Purification: Immunogen affinity purified
- Dilution: WB: 1:200-1:1000; IHC: 1:50-1:500; IF: 1:50-1:500
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 11 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)