S100A8 antibody

• Background :

  The protein encoded by this gene is a member of the S100 family of proteins containing 2 EF-hand calcium-binding motifs. S100 proteins are localized in the cytoplasm and/or nucleus of a wide range of cells, and involved in the regulation of a number of cellular processes such as cell cycle progression and differentiation. S100 genes include at least 13 members which are located as a cluster on chromosome 1q21. This protein may function in the inhibition of casein kinase and as a cytokine. Altered expression of this protein is associated with the disease cystic fibrosis. Multiple transcript variants encoding different isoforms have been found for this gene.

• Synonyms :

  Protein S100-A8|Calgranulin-A|Calprotectin L1L subunit|Cystic fibrosis antigen (CFAG) |Leukocyte L1 complex light chain|Migration inhibitory factor-related protein 8 (MRP-8, p8) |S100 calcium-binding protein A8|Urinary stone protein band A|S100A8|CAGA|CFAG|MRP8

• Gene ID :

  6279

• UniProt :

  P05109

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  S100 calcium binding protein A8

• Target :

  S100A8

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Immunology

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IHC: 1:50-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  10 kDa

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC