RTN3 antibody

• Background:

  May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules (PubMed:25612671) .

• Synonyms:

  Reticulon-3|Homolog of ASY protein (HAP) |Neuroendocrine-specific protein-like 2 (NSP-like protein 2) |Neuroendocrine-specific protein-like II (NSP-like protein II, NSPLII) |RTN3|ASYIP|NSPL2

• Gene ID:

  10313

• UniProt:

  O95197

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Reticulon 3

• Target:

  RTN3

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IP

• Field of Research:

  Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:3000; IP: 1:200-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  24 kDa, 113 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IP