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RTN3 antibody

CAT: 0710-FNab07523Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07523Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
May be involved in membrane trafficking in the early secretory pathway. Inhibits BACE1 activity and amyloid precursor protein processing. May induce caspase-8 cascade and apoptosis. May favor BCL2 translocation to the mitochondria upon endoplasmic reticulum stress. In case of enteroviruses infection, RTN3 may be involved in the viral replication or pathogenesis. Induces the formation of endoplasmic reticulum tubules (PubMed:25612671) .
Synonyms
Reticulon-3|Homolog of ASY protein (HAP) |Neuroendocrine-specific protein-like 2 (NSP-like protein 2) |Neuroendocrine-specific protein-like II (NSP-like protein II, NSPLII) |RTN3|ASYIP|NSPL2
Gene ID
10313
UniProt
O95197
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Reticulon 3
Target
RTN3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:3000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
24 kDa, 113 kDa
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP

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