RPLP0 antibody

CAT: 0710-FNab07447Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab07447Size:100 µg

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Background

Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein, which is the functional equivalent of the E. coli L10 ribosomal protein, belongs to the L10P family of ribosomal proteins. It is a neutral phosphoprotein with a C-terminal end that is nearly identical to the C-terminal ends of the acidic ribosomal phosphoproteins P1 and P2. The P0 protein can interact with P1 and P2 to form a pentameric complex consisting of P1 and P2 dimers, and a P0 monomer. The protein is located in the cytoplasm. Transcript variants derived from alternative splicing exist; they encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome.

Synonyms

Large ribosomal subunit protein uL10|60S acidic ribosomal protein P0|60S ribosomal protein L10E|RPLP0

Gene ID

6175

UniProt

P05388

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Ribosomal protein, large, P0

Target

RPLP0

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, IF

Field of Research

Metabolism

Purification

Immunogen affinity purified

Dilution

WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

37 kDa

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, IF

UniProtKB · P05388

Large ribosomal subunit protein uL10

RLA0_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: P05388
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: RPLP0
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q3B7A4, Q9BVK4

Protein keywords

Technical term

3D-structureDirect protein sequencingProteomics identificationReference proteome

Coding sequence diversity

Alternative splicing

Cellular component

CytoplasmNucleus

PTM

Isopeptide bondPhosphoproteinUbl conjugation

Molecular function

RibonucleoproteinRibosomal protein

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