RFC4 antibody

CAT: 0710-FNab07250Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab07250Size:100 µg
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Background
The elongation of primed DNA templates by DNA polymerase delta and DNA polymerase epsilon requires the accessory proteins proliferating cell nuclear antigen (PCNA) and replication factor C (RFC) . RFC, also named activator 1, is a protein complex consisting of five distinct subunits of 140, 40, 38, 37, and 36 kD. This gene encodes the 37 kD subunit. This subunit forms a core complex with the 36 and 40 kDa subunits. The core complex possesses DNA-dependent ATPase activity, which was found to be stimulated by PCNA in an in vitro system. Alternatively spliced transcript variants encoding the same protein have been reported.
Synonyms
Replication factor C subunit 4|Activator 1 37 kDa subunit (A1 37 kDa subunit) |Activator 1 subunit 4|Replication factor C 37 kDa subunit (RF-C 37 kDa subunit, RFC37) |RFC4
Gene ID
5984
UniProt
P35249
Host
Rabbit
Reactivity
Human, Rat
Immunogen
Replication factor C (activator 1) 4, 37kDa
Target
RFC4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100; IP: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
38 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

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