RECK antibody

• Background:

  Negatively regulates matrix metalloproteinase-9 (MMP-9) by suppressing MMP-9 secretion and by direct inhibition of its enzymatic activity. RECK down-regulation by oncogenic signals may facilitate tumor invasion and metastasis. Appears to also regulate MMP-2 and MT1-MMP, which are involved in cancer progression.

• Synonyms:

  Reversion-inducing cysteine-rich protein with Kazal motifs (hRECK) |Suppressor of tumorigenicity 15 protein|RECK|ST15

• Gene ID:

  8434

• UniProt:

  O95980

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Reversion-inducing-cysteine-rich protein with kazal motifs

• Target:

  RECK

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Cell Division and Proliferation, cancer

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  110 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB

• Immunogen Sequence:

  110-210AA