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RCC1 antibody

CAT: 0710-FNab07207Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07207Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Guanine-nucleotide releasing factor that promotes the exchange of Ran-bound GDP by GTP. Involved in the regulation of onset of chromosome condensation in the S phase. Binds both to the nucleosomes and double-stranded DNA. RCC1-Ran complex (together with other proteins) acts as a component of a signal transmission pathway that detects unreplicated DNA. Plays a key role in nucleo-cytoplasmic transport, mitosis and nuclear-envelope assembly.
Synonyms
Regulator of chromosome condensation|Cell cycle regulatory protein|Chromosome condensation protein 1|RCC1|CHC1
Gene ID
1104
UniProt
P18754
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
SNHG3-RCC1 readthrough transcript
Target
RCC1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Cancer, Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC