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RBBP7 antibody

CAT: 0710-FNab07147Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07147Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.
Synonyms
Histone-binding protein RBBP7|Histone acetyltransferase type B subunit 2|Nucleosome-remodeling factor subunit RBAP46|Retinoblastoma-binding protein 7 (RBBP-7) |Retinoblastoma-binding protein p46|RBBP7|RBAP46
Gene ID
5931
UniProt
Q16576
Host
Rabbit
Reactivity
Human
Immunogen
Retinoblastoma binding protein 7
Target
RBBP7
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Epigenetics, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
48 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

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