RBBP7 antibody

• Background:

  This protein is a ubiquitously expressed nuclear protein and belongs to a highly conserved subfamily of WD-repeat proteins. It is found among several proteins that binds directly to retinoblastoma protein, which regulates cell proliferation. The encoded protein is found in many histone deacetylase complexes, including mSin3 co-repressor complex. It is also present in protein complexes involved in chromatin assembly. This protein can interact with BRCA1 tumor-suppressor gene and may have a role in the regulation of cell proliferation and differentiation. Two transcript variants encoding different isoforms have been found for this gene.

• Synonyms:

  Histone-binding protein RBBP7|Histone acetyltransferase type B subunit 2|Nucleosome-remodeling factor subunit RBAP46|Retinoblastoma-binding protein 7 (RBBP-7)|Retinoblastoma-binding protein p46|RBBP7|RBAP46

• Gene ID:

  5931

• UniProt:

  Q16576

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  retinoblastoma binding protein 7

• Target:

  RBBP7

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF, IP

• Field of Research:

  Epigenetics, Metabolism, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200; ChIP: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  48 kDa

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• CAS Number:

  9007-83-4