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RARG antibody

CAT: 0710-FNab07122Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab07122Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RAR/RXR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence of ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. Required for limb bud development. In concert with RARA or RARB, required for skeletal growth, matrix homeostasis and growth plate function (By similarity) .
Synonyms
Retinoic acid receptor gamma (RAR-gamma) |Nuclear receptor subfamily 1 group B member 3|RARG|NR1B3
Gene ID
5916
UniProt
P13631
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Retinoic acid receptor, gamma
Target
RARG
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Cancer, Signal Transduction, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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