RAB3GAP1 antibody

• Background :

  Probable catalytic subunit of a GTPase activating protein that has specificity for Rab3 subfamily (RAB3A, RAB3B, RAB3C and RAB3D) . Rab3 proteins are involved in regulated exocytosis of neurotransmitters and hormones. Specifically converts active Rab3-GTP to the inactive form Rab3-GDP. Required for normal eye and brain development. May participate in neurodevelopmental processes such as proliferation, migration and differentiation before synapse formation, and non-synaptic vesicular release of neurotransmitters.

• Synonyms :

  Rab3 GTPase-activating protein catalytic subunit|RAB3 GTPase-activating protein 130 kDa subunit|Rab3-GAP p130 (Rab3-GAP) |RAB3GAP1|KIAA0066|RAB3GAP

• Gene ID :

  22930

• UniProt :

  Q15042

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  RAB3 GTPase activating protein subunit 1 (catalytic)

• Target :

  RAB3GAP1

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC, IF, IP

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  130 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC, IF, IP

• Immunogen Sequence :

  500-800aa