Products for Research Use Only
RegisterLogin

PTBP1 antibody

CAT: 0710-FNab06906Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab06906Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs) . The hnRNPs are RNA-binding proteins and they complex with heterogeneous nuclear RNA (hnRNA) . These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has four repeats of quasi-RNA recognition motif (RRM) domains that bind RNAs. This protein binds to the intronic polypyrimidine tracts that requires pre-mRNA splicing and acts via the protein degradation ubiquitin-proteasome pathway. It may also promote the binding of U2 snRNP to pre-mRNAs. This protein is localized in the nucleoplasm and it is also detected in the perinucleolar structure. Alternatively spliced transcript variants encoding different isoforms have been described.
Synonyms
Polypyrimidine tract-binding protein 1 (PTB) |57 kDa RNA-binding protein PPTB-1|Heterogeneous nuclear ribonucleoprotein I (hnRNP I) |PTBP1|PTB
Gene ID
5725
UniProt
P26599
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Polypyrimidine tract binding protein 1
Target
PTBP1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:1000; IHC: 1:100 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
57 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

Related Products

CatalogName
P1712-01Recombinant Human PTBP1
FNab06908PTBP2 antibody
FNab11062CA125 antibody (capture antibody)
FNab11060AFP antibody (capture antibody)
FNab11045-01CEA antibody (detection antibody)
FNab11061CA125 antibody (detection antibody)
FNab11059AFP antibody (detection antibody)
FNab11046-01CEA antibody (capture antibody)
FNab09471WAS antibody
FNab11063CA19-9 antibody (detection antibody)

Alternative Products

CatalogName
70R-19616PTBP1 antibody

Popular Products