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PSMB10 antibody

CAT: 0710-FNab06869Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06869Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the proteasome B-type family, also known as the T1B family, that is a 20S core beta subunit. Proteolytic processing is required to generate a mature subunit. Expression of this gene is induced by gamma interferon, and this gene product replaces catalytic subunit 2 (proteasome beta 7 subunit) in the immunoproteasome.
Synonyms
Proteasome subunit beta type-10|Low molecular mass protein 10|Macropain subunit MECl-1|Multicatalytic endopeptidase complex subunit MECl-1|Proteasome MECl-1|Proteasome subunit beta-2i|PSMB10|LMP10|MECL1
Gene ID
5699
UniProt
P40306
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Proteasome (prosome, macropain) subunit, beta type, 10
Target
PSMB10
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
29 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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