SELP antibody
CAT:
710-FNab06851
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
SELP antibody
- Background: P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.
- Synonyms: P-selectin|CD62 antigen-like family member P|Granule membrane protein 140 (GMP-140)|Leukocyte-endothelial cell adhesion molecule 3 (LECAM3)|Platelet activation dependent granule-external membrane protein (PADGEM)|SELP|GMRP|GRMP
- CAS Number: 9007-83-4
- UniProt: P16109
- Host: Rabbit
- Reactivity: Human
- Immunogen: selectin P(granule membrane protein 140kDa, antigen CD62)
- Target: SELP
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, IHC, WB
- Field of Research: Immunology, Cardiovascular, Signal Transduction
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500-1:2000; IHC: 1:20-1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 100 kDa, 150kD
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)