SELP antibody

CAT: 0710-FNab06851Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab06851Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

P-selectin, also known as GMP140 or CD62P, is a transmembrane glycoprotein that mediates the interaction of activated endothelial cells or platelets with leukocytes. It is an adhesion molecule involved in the pathogenesis of inflammation, thrombosis, and oncogenesis. P-selectin is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. Upon cell activation by agonists, P-selectin is transported rapidly to the cell surface.

Synonyms

UniProt

P16109

Host

Rabbit

Reactivity

Human

Immunogen

Selectin P (granule membrane protein 140kDa, antigen CD62)

Target

SELP

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, IHC, WB

Field of Research

Immunology, Cardiovascular, Signal Transduction

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:2000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

100 kDa, 150kD

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, IHC, WB

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