Products for Research Use Only
RegisterLogin

PRR5 antibody

CAT: 0710-FNab06830Size: 100 µgDry Ice: NoHazardous: No
Product image 1
1 / 1
CAT#:0710-FNab06830Size:100 µg
Selected
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
Quick Request Actions
Background
Subunit of mTORC2, which regulates cell growth and survival in response to hormonal signals. mTORC2 is activated by growth factors, but, in contrast to mTORC1, seems to be nutrient-insensitive. mTORC2 seems to function upstream of Rho GTPases to regulate the actin cytoskeleton, probably by activating one or more Rho-type guanine nucleotide exchange factors. mTORC2 promotes the serum-induced formation of stress-fibers or F-actin. mTORC2 plays a critical role in AKT1 'Ser-473' phosphorylation, which may facilitate the phosphorylation of the activation loop of AKT1 on 'Thr-308' by PDK1 which is a prerequisite for full activation. mTORC2 regulates the phosphorylation of SGK1 at 'Ser-422'. mTORC2 also modulates the phosphorylation of PRKCA on 'Ser-657'. PRR5 plays an important role in regulation of PDGFRB expression and in modulation of platelet-derived growth factor signaling. May act as a tumor suppressor in breast cancer.
Synonyms
Proline-rich protein 5|Protein observed with Rictor-1 (Protor-1) |PRR5|PROTOR1
Gene ID
55615
UniProt
P85299
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Proline rich 5 (renal)
Target
PRR5
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF, IP
Field of Research
Epigenetics
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
33 kDa, 50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF, IP

Related Products

CatalogName
FNab06829PRR4 antibody
EH3661Human PRR4 (Proline Rich Protein 4, Lacrimal) ELISA Kit
FNab11062CA125 antibody (capture antibody)
FNab11060AFP antibody (capture antibody)
FNab11045-01CEA antibody (detection antibody)
FNab11061CA125 antibody (detection antibody)
FNab11059AFP antibody (detection antibody)
FNab11046-01CEA antibody (capture antibody)
FNab09471WAS antibody
FNab11063CA19-9 antibody (detection antibody)

Alternative Products

CatalogName
70R-9436PRR5 antibody

Popular Products