PRPF8 antibody

• Background:

  Pre-mRNA splicing occurs in 2 sequential transesterification steps. The protein encoded by this gene is a component of both U2- and U12-dependent spliceosomes, and found to be essential for the catalytic step II in pre-mRNA splicing process. It contains several WD repeats, which function in protein-protein interactions. This protein has a sequence similarity to yeast Prp8 protein. This gene is a candidate gene for autosomal dominant retinitis pigmentosa.

• Synonyms:

  Pre-mRNA-processing-splicing factor 8|220 kDa U5 snRNP-specific protein|PRP8 homolog|Splicing factor Prp8|p220|PRPF8|PRPC8

• Gene ID:

  10594

• UniProt:

  Q6P2Q9

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  PRP8 pre-mRNA processing factor 8 homolog

• Target:

  PRPF8

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Neuroscience, Metabolism, Epigenetics

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:1000; IHC: 1:50 - 1:100

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  274 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC