PRMT5 antibody

• Background:

  This gene encodes an enzyme that belongs to the methyltransferase family. The encoded protein catalyzes the transfer of methyl groups to the amino acid arginine, in target proteins that include histones, transcriptional elongation factors and the tumor suppressor p53. This gene plays a role in several cellular processes, including transcriptional regulation, and the assembly of small nuclear ribonucleoproteins. A pseudogene of this gene has been defined on chromosome 4. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Synonyms:

  Protein arginine N-methyltransferase 5 (PRMT5) |72 kDa ICln-binding protein|Histone-arginine N-methyltransferase PRMT5|Jak-binding protein 1|Shk1 kinase-binding protein 1 homolog (SKB1 homolog, SKB1Hs) |Protein arginine N-methyltransferase 5, N-terminally processed|PRMT5|HRMT1L5|IBP72|JBP1|SKB1

• Gene ID:

  10419

• UniProt:

  O14744

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat, Monkey

• Immunogen:

  Protein arginine methyltransferase 5

• Target:

  PRMT5

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Epigenetics, Signal Transduction, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  70 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC

• Immunogen Sequence:

  76-291aa