PPP6C antibody

• Background:

  Catalytic subunit of protein phosphatase 6 (PP6) . PP6 is a component of a signaling pathway regulating cell cycle progression in response to IL2 receptor stimulation. N-terminal domain restricts G1 to S phase progression in cancer cells, in part through control of cyclin D1. Downregulates MAP3K7 kinase activation of the IL1 signaling pathway by dephosphorylation of MAP3K7.

• Synonyms:

  Serine/threonine-protein phosphatase 6 catalytic subunit (PP6C) |Serine/threonine-protein phosphatase 6 catalytic subunit, N-terminally processed|PPP6C|PPP6

• Gene ID:

  5537

• UniProt:

  O00743

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Protein phosphatase 6, catalytic subunit

• Target:

  PPP6C

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  35 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB