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PPP2R1B antibody

CAT: 0710-FNab06715Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06715Size:100 µg
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Background
This gene encodes a constant regulatory subunit of protein phosphatase 2. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The constant regulatory subunit A serves as a scaffolding molecule to coordinate the assembly of the catalytic subunit and a variable regulatory B subunit. This gene encodes a beta isoform of the constant regulatory subunit A. Mutations in this gene have been associated with some lung and colon cancers. Alternatively spliced transcript variants have been described.
Synonyms
Serine/threonine-protein phosphatase 2A 65 kDa regulatory subunit A beta isoform|PP2A subunit A isoform PR65-beta|PP2A subunit A isoform R1-beta|PPP2R1B
Gene ID
5519
UniProt
P30154
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein phosphatase 2 (formerly 2A), regulatory subunit A, beta isoform
Target
PPP2R1B
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
65 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB

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