PPIL2 antibody

• Background:

  May catalyze the cis-trans isomerization of proline imidic peptide bonds in oligopeptides thereby assisting the folding of proteins (By similarity) . May also function as a chaperone, playing a role in transport to the cell membrane of BSG for instance (PubMed:15946952) . May also have a protein ubiquitin ligase activity acting as an E3 ubiquitin protein ligase or as an ubiquitin-ubiquitin ligase promoting elongation of ubiquitin chains on substrates. By mediating 'Lys-48'-linked polyubiquitination of proteins could target them for proteasomal degradation (PubMed:11435423) .

• Synonyms:

  RING-type E3 ubiquitin-protein ligase PPIL2|CYC4|Cyclophilin-60 (Cyclophilin-like protein Cyp-60, Cyp60, hCyP-60) |Probable inactive peptidyl-prolyl cis-trans isomerase-like 2 (PPIase) |Rotamase PPIL2|PPIL2

• Gene ID:

  23759

• UniProt:

  Q13356

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Peptidylprolyl isomerase (cyclophilin) -like 2

• Target:

  PPIL2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB

• Field of Research:

  Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  59 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB