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POLG2 antibody

CAT: 0710-FNab06611Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06611Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the processivity subunit of the mitochondrial DNA polymerase gamma. The encoded protein forms a heterotrimer containing one catalytic subunit and two processivity subunits. This protein enhances DNA binding and promotes processive DNA synthesis. Mutations in this gene result in autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions.
Synonyms
DNA polymerase subunit gamma-2, mitochondrial|DNA polymerase gamma accessory 55 kDa subunit (p55) |Mitochondrial DNA polymerase accessory subunit|MtPolB|PolG-beta|POLG2|MTPOLB
Gene ID
11232
UniProt
Q9UHN1
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Polymerase (DNA directed), gamma 2, accessory subunit
Target
POLG2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, IHC, WB, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:100
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, IHC, WB, IF

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