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POFUT2 antibody

CAT: 0710-FNab06603Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06603Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Catalyzes the reaction that attaches fucose through an O-glycosidic linkage to a conserved serine or threonine residue in the consensus sequence C1-X (2,3) -S/T-C2-X (2) -G of thrombospondin type 1 repeats where C1 and C2 are the first and second cysteines, respectively. O-fucosylates members of several protein families including the ADAMTS family, the thrombosporin (TSP) and spondin families. The O-fucosylation of TSRs is also required for restricting epithelial to mesenchymal transition (EMT), maintaining the correct patterning of mesoderm and localization of the definite endoderm (By similarity) . Required for the proper secretion of ADAMTS family members such as ADAMSL1 and ADAMST13.
Synonyms
GDP-fucose protein O-fucosyltransferase 2|Peptide-O-fucosyltransferase 2 (O-FucT-2) |POFUT2|C21orf80|FUT13|KIAA0958
Gene ID
23275
UniProt
Q9Y2G5
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Protein O-fucosyltransferase 2
Target
POFUT2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
49 kDa, 50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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