PODXL antibody

CAT: 0710-FNab06597Size: 100 µgDry Ice: NoHazardous: No

1 / 1

CAT#:0710-FNab06597Size:100 µg

Selected

24/48H Stock Items & 2 to 6 Weeks non Stock Items.

Quick Request Actions

Background

Podocalyxin, also known as podocalyxin-like protein 1 (PODXL or PCLP1), is a transmembrane glycoprotein belonging to the CD34 family of sialomucins. Podocalyxin was originally identified as the major sialoprotein on podocytes of the kidney glomerulus, but was later found to be expressed on vascular endothelial cells and early hematopoietic progenitors. It Involved in the regulation of both adhesion and cell morphology. In addition, podocalyxin is highly expressed in embryonic stem cells and aberrant expression of podocalyxin has been implicated in a wide range of cancers.

Synonyms

Gene ID

5420

UniProt

O00592

Host

Rabbit

Reactivity

Human, Mouse

Immunogen

Podocalyxin

Target

PODXL

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB, IHC, FC

Field of Research

Stem Cells, Cardiovascular

Purification

Immunogen affinity purified

Dilution

WB: 1:500-1:1000; IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

59 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB, IHC, FC

Immunogen Sequence

23-340aa

UniProtKB · O00592

Podocalyxin

PODXL_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: O00592
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: PODXL
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: Precursor
Secondary accessions: A6NHX8, Q52LZ7, Q53ER6

Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

Cell adhesion

Cellular component

Cell membraneCell projectionMembrane

Technical term

Direct protein sequencingProteomics identificationReference proteome

PTM

GlycoproteinPhosphoprotein

Domain

SignalTransmembraneTransmembrane helix

Related Products

Catalog	Name
P1580-01	Recombinant Human PODXL
P1839-01	Recombinant Mouse Podxl
EH1042	Human PODXL (Podocalyxin) ELISA Kit
EM0452	Mouse Podxl (Podocalyxin) ELISA Kit
QT-EM0452	Mouse Podxl (Podocalyxin) QuickTest ELISA Kit
FNab06600	PODXL2 antibody
EH5344	Human PODXL2 (Podocalyxin-like protein 2) ELISA Kit
FNab11062	CA125 antibody (capture antibody)
FNab11060	AFP antibody (capture antibody)
FNab11045-01	CEA antibody (detection antibody)

Alternative Products

Catalog	Name
GTR18081482-01	PODXL Antibody