PLCD3 antibody

• Background :

  Hydrolyzes the phosphatidylinositol 4,5-bisphosphate (PIP2) to generate 2 second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) . DAG mediates the activation of protein kinase C (PKC), while IP3 releases Ca (2+) from intracellular stores. Essential for trophoblast and placental development. May participate in cytokinesis by hydrolyzing PIP2 at the cleavage furrow.

• Synonyms :

  1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase delta-3|Phosphoinositide phospholipase C-delta-3|Phospholipase C-delta-3 (PLC-delta-3) |PLCD3|KIAA1964

• Gene ID :

  113026

• UniProt :

  Q8N3E9

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  Phospholipase C, delta 3

• Target :

  PLCD3

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB

• Field of Research :

  Signal Transduction, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:2000

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  85 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB