Alpidem

• Description:

  Alpidem selectively binds to α1β2γ2 subunit-containing GABAA receptor with an IC50 of 17 nM and exerts anxiolytic effect[1].

• UNSPSC:

  12352005

• Hazard Statement:

  H302, H315, H319, H335

• Target:

  GABA Receptor

• Type:

  Reference compound

• Related Pathways:

  Membrane Transporter/Ion Channel; Neuronal Signaling

• Applications:

  Neuroscience-Neuromodulation

• Field of Research:

  Neurological Disease

• Assay Protocol:

  https://www.medchemexpress.com/alpidem.html

• Purity:

  99.70

• Solubility:

  DMSO : 25 mg/mL (ultrasonic)

• Smiles:

  O=C (N (CCC) CCC) CC1=C (C2=CC=C (Cl) C=C2) N=C3C=CC (Cl) =CN31

• Molecular Formula:

  C21H23Cl2N3O

• Molecular Weight:

  404.34

• Precautions:

  H302, H315, H319, H335

• References & Citations:

  [1]Faure-Halley C, et al. Expression and properties of recombinant alpha 1 beta 2 gamma 2 and alpha 5 beta 2 gamma 2 forms of the rat GABAA receptor. Eur J Pharmacol. 1993 Aug 15;246 (3) :283-7.

• Shipping Conditions:

  Room Temperature

• Storage Conditions:

  -20°C, 3 years; 4°C, 2 years (Powder)

• Scientific Category:

  Reference compound1

• Clinical Information:

  Launched

• CAS Number:

  82626-01-5