PHOX2B antibody

CAT: 0710-FNab06409Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab06409Size:100 µg
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Background
Involved in the development of several major noradrenergic neuron populations, including the locus coeruleus. Transcription factor which could determine a neurotransmitter phenotype in vertebrates. Enhances second-messenger-mediated activation of the dopamine beta-hydrolase and c-fos promoters, and of several enhancers including cAMP-response element and serum-response element.
Synonyms
Paired mesoderm homeobox protein 2B|Neuroblastoma Phox (NBPhox) |PHOX2B homeodomain protein|Paired-like homeobox 2B|PHOX2B|PMX2B
Gene ID
8929
UniProt
Q99453
Host
Mouse
Reactivity
Human, Mouse
Immunogen
Paired-like homeobox 2b
Target
PHOX2B
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, IHC, WB
Field of Research
Neuroscience, Epigenetics, Metabolism, Developmental biology
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:5000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
35 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
2B0
Tested Applications
ELISA, IHC, WB
Immunogen Sequence
60-314aa

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