CDK14 antibody

• Background :

  PFTK1 is a Cdc2-related protein kinase, also named as PFTAIRE1, CDK14 and belongs to the CMGC Ser/Thr protein kinase family and CDC2/CDKX subfamily. It acts as a cyclin-dependent kinases that regulates cell cycle progression and cell proliferation. The PFTK1 protein shows high homology with mouse Pftaire1, a Cdc2-related protein expressed primarily in the postnatal and adult nervous system (PMID:9202329) . The protein contains 2 predicted nuclear localization signals that the N-terminal nuclear localization signals do not play a role in vivo (PMID:11313143) . It has 3 isoforms produced by alternative splicing. This antibody is specific to PFTK1.

• Synonyms :

  Cyclin-dependent kinase 14|Cell division protein kinase 14|Serine/threonine-protein kinase PFTAIRE-1 (hPFTAIRE1) |CDK14|KIAA0834|PFTK1

• UniProt :

  O94921

• Host :

  Rabbit

• Reactivity :

  Human, Mouse, Rat

• Immunogen :

  PFTAIRE protein kinase 1

• Target :

  CDK14

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IHC

• Field of Research :

  Cell Division and Proliferation, Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500-1:5000; IHC: 1:50-1:500

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  48-53 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IHC