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PFKM antibody

CAT: 0710-FNab06341Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06341Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1, 6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described.
Synonyms
ATP-dependent 6-phosphofructokinase, muscle type (ATP-PFK, PFK-M) |6-phosphofructokinase type A|Phosphofructo-1-kinase isozyme A (PFK-A) |Phosphohexokinase|PFKM|PFKX
Gene ID
5213
UniProt
P08237
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Phosphofructokinase, muscle
Target
PFKM
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
85 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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