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PFKFB3-Specific antibody

CAT: 0710-FNab06339Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06339Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
PFKFB3, also named as NY-REN-56 and iPFK-2, plays a role in glucose metabolism. It synthesis and degradation of fructose 2,6-bisphosphate. Endogenously generated adenosine cooperates with bacterial components to increase PFKFB3 isozyme activity, resulting in greater fructose 2,6-bisphosphate accumulation. PFKFB3 is required for increased growth, metabolic activity and is regulated through active JAK2 and STAT5. This antibody is specific to PFKFB3.
Synonyms
6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 (6PF-2-K/Fru-2,6-P2ase 3, PFK/FBPase 3) |6PF-2-K/Fru-2,6-P2ase brain/placenta-type isozyme|Renal carcinoma antigen NY-REN-56|iPFK-2|PFKFB3
Gene ID
5209
UniProt
Q16875
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3
Target
PFKFB3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:50-1:200; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
58 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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