PDCD4 antibody

CAT: 0710-FNab06240Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab06240Size:100 µg
Selected
AVAILABILITY
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity) .
Synonyms
Programmed cell death protein 4|Neoplastic transformation inhibitor protein|Nuclear antigen H731-like|Protein 197/15a|PDCD4|H731
Gene ID
27250
UniProt
Q53EL6
Host
Mouse
Reactivity
Human
Immunogen
Programmed cell death 4 (neoplastic transformation inhibitor)
Target
PDCD4
Clonality
Monoclonal
Isotype
IgG1
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:4000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
56 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
3B7
Tested Applications
ELISA, WB, IHC