PCSK4 antibody

CAT: 0710-FNab06225Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab06225Size:100 µg
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Background
Proprotein convertase involved in the processing of hormone and other protein precursors at sites comprised of pairs of basic amino acid residues (By similarity) . In males, important for ADAM2 processing as well as other acrosomal proteins with roles in fertilization and critical for normal fertilization events such as sperm capacitation, acrosome reaction and binding of sperm to zona pellucida (By similarity) . Plays also a role in female fertility, involved in the regulation of trophoblast migration and placental development, may be through the proteolytical processing and activation of proteins such as IGF2 (PubMed:16040806) . May also participate to folliculogenesis in the ovaries (By similarity) .
Synonyms
Proprotein convertase subtilisin/kexin type 4|Proprotein convertase 4 (PC4) |PCSK4|PC4
Gene ID
54760
UniProt
Q6UW60
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Proprotein convertase subtilisin/kexin type 4
Target
PCSK4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Signal Transduction, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
54 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB
Immunogen Sequence
514-755aa

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