PARP1 antibody
CAT:
710-FNab06151
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
PARP1 antibody
- Background: This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
- Synonyms: Poly [ADP-ribose] polymerase 1 (PARP-1)|ADP-ribosyltransferase diphtheria toxin-like 1 (ARTD1)|DNA ADP-ribosyltransferase PARP1|NAD(+) ADP-ribosyltransferase 1 (ADPRT 1)|Poly[ADP-ribose] synthase 1|Protein poly-ADP-ribosyltransferase PARP1|Poly [ADP-ribose] polymerase 1, processed C-terminus Alternative names: Poly [ADP-ribose] polymerase 1, 89-kDa form|Poly [ADP-ribose] polymerase 1, processed N-terminus (NT-PARP-1) Alternative names: Poly [ADP-ribose] polymerase 1, 24-kDa form|Poly [ADP-ribose] polymerase 1, 28-kDa form|PARP1|ADPRT|PPOL
- CAS Number: 9007-83-4
- Gene ID: 142
- UniProt: P09874
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: poly (ADP-ribose) polymerase 1
- Target: PARP1
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB, IHC, IF
- Field of Research: Metabolism
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 115 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)