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PAG1 antibody

CAT: 0710-FNab06112Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab06112Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Negatively regulates TCR (T-cell antigen receptor) -mediated signaling in T-cells and FCER1 (high affinity immunoglobulin epsilon receptor) -mediated signaling in mast cells. Promotes CSK activation and recruitment to lipid rafts, which results in LCK inhibition. Inhibits immunological synapse formation by preventing dynamic arrangement of lipid raft proteins. May be involved in cell adhesion signaling.
Synonyms
Phosphoprotein associated with glycosphingolipid-enriched microdomains 1|Csk-binding protein|Transmembrane adapter protein PAG|Transmembrane phosphoprotein Cbp|PAG1|CBP|PAG
Gene ID
55824
UniProt
Q9NWQ8
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
Phosphoprotein associated with glycosphingolipid microdomains 1
Target
PAG1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Immunology, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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