TP63 antibody

• Background:

  TP63, also named KET, P63, P73H, P73L and TP73L, belongs to the p53 family. It is a homologue of the tumor suppressor p53 and p73 genes. It is involved in malignancy acquisition and maintenance of cells. Unlike p53, the p63 gene encodes multiple isotypes with remarkably divergent abilities to transactivate p53 reporter genes and induce apoptosis. TP63 acts as a sequence specific DNA binding transcriptional activator or repressor. TP63 has 12 isoforms with MW 40kd (P40), 50kd (P60),63kd (P63) and 73kd (P73L) . It is Nuclear stain.

• Synonyms:

  Tumor protein 63 (p63) |Chronic ulcerative stomatitis protein (CUSP) |Keratinocyte transcription factor KET|Transformation-related protein 63 (TP63) |Tumor protein p73-like (p73L) |p40|p51|TP63|KET|P63|P73H|P73L|TP73L

• Gene ID:

  8626

• UniProt:

  Q9H3D4

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Tumor protein p63

• Target:

  TP63

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Metabolism, Immunology, Cancer, Stem Cells, Cell Division and Proliferation

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:20 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  45-75 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF

• Immunogen Sequence:

  421-680aa