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OPRL1 antibody

CAT: 0710-FNab05997Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05997Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
G-protein coupled opioid receptor that functions as receptor for the endogenous neuropeptide nociceptin. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors. Signaling via G proteins mediates inhibition of adenylate cyclase activity and calcium channel activity. Arrestins modulate signaling via G proteins and mediate the activation of alternative signaling pathways that lead to the activation of MAP kinases. Plays a role in modulating nociception and the perception of pain. Plays a role in the regulation of locomotor activity by the neuropeptide nociceptin.
Synonyms
Nociceptin receptor|Kappa-type 3 opioid receptor (KOR-3) |Orphanin FQ receptor|OPRL1|OOR|ORL1
Gene ID
4987
UniProt
P41146
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Opiate receptor-like 1
Target
OPRL1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IP
Field of Research
Neuroscience, Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IP
Immunogen Sequence
Peptide, Cytoplasmic domain

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