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OGG1 antibody

CAT: 0710-FNab05980Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05980Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Many alternative splice variants for this gene have been described, but the full-length nature for every variant has not been determined.
Synonyms
N-glycosylase/DNA lyase|OGG1|MMH|MUTM|OGH1
Gene ID
4968
UniProt
O15527
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
8-oxoguanine DNA glycosylase
Target
OGG1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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