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POU5F1 antibody

CAT: 0710-FNab05963Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05963Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene encodes a transcription factor containing a POU homeodomain that plays a key role in embryonic development and stem cell pluripotency. Aberrant expression of this gene in adult tissues is associated with tumorigenesis. This gene can participate in a translocation with the Ewing's sarcoma gene on chromosome 21, which also leads to tumor formation. Alternative splicing, as well as usage of alternative AUG and non-AUG translation initiation codons, results in multiple isoforms. One of the AUG start codons is polymorphic in human populations. Related pseudogenes have been identified on chromosomes 1, 3, 8, 10, and 12.
Synonyms
POU domain, class 5, transcription factor 1|Octamer-binding protein 3 (Oct-3) |Octamer-binding protein 4 (Oct-4) |Octamer-binding transcription factor 3 (OTF-3) |POU5F1|OCT3|OCT4|OTF3
Gene ID
5460
UniProt
Q01860
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
POU class 5 homeobox 1
Target
POU5F1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC, IF
Field of Research
Cancer, Immunology, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
50 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, IF

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