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NT5E antibody

CAT: 0710-FNab05878Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05878Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
NT5E (5'-nucleotidase) is also named as NT5, NTE, CD73, ecto-5'-nucleotidase, and belongs to the 5'-nucleotidase family. It catalyzes the conversion at neutral pH of purine 5-prime mononucleotides to nucleosides, the preferred substrate being AMP.The enzyme occurs mainly as a dimer and the wide distribution of NT5E in the rat hippocampus, suggesting their involvement in the control of the purinergic signaling (PMID:17619139) . This protein has two isoforms with the molecular weight of 63 kDa and 58 kDa and four glycosylation sites with a signalpeptide. It can exsit as a dimer (PMID:17619139) . It can be detected the band of 55 kDa,64 kDa, 70 kDa, 110 kDa by western blot (PMID:17619139; 12370277; 21533188) . Defects in NT5E are the cause of calcification of joints and arteries (CALJA) .
Synonyms
5'-nucleotidase (5'-NT) |5'-deoxynucleotidase|Ecto-5'-nucleotidase|IMP-specific 5'-nucleotidase|Thymidylate 5'-phosphatase|NT5E|NT5|NTE
Gene ID
4907
UniProt
P21589
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
5'-nucleotidase, ecto (CD73)
Target
NT5E
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB,IHC,FC
Field of Research
Metabolism, Cardiovascular, Immunology, Cancer, Stem Cells
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:5000; IHC: 1:50-1:500
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
63 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC, FC

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