NCF2 antibody

• Background:

  This gene encodes neutrophil cytosolic factor 2, the 67-kilodalton cytosolic subunit of the multi-protein NADPH oxidase complex found in neutrophils. This oxidase produces a burst of superoxide which is delivered to the lumen of the neutrophil phagosome. Mutations in this gene, as well as in other NADPH oxidase subunits, can result in chronic granulomatous disease, a disease that causes recurrent infections by catalase-positive organisms. Alternative splicing results in multiple transcript variants encoding different isoforms.

• Synonyms:

  Neutrophil cytosol factor 2 (NCF-2) |67 kDa neutrophil oxidase factor|NADPH oxidase activator 2|Neutrophil NADPH oxidase factor 2|p67-phox|NCF2|NOXA2|P67PHOX

• Gene ID:

  4688

• UniProt:

  P19878

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  Neutrophil cytosolic factor 2

• Target:

  NCF2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IF

• Field of Research:

  Cancer, Metabolism, Immunology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200; IF: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  68 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IF