NLRP2 antibody

CAT: 0710-FNab05758Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab05758Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Suppresses TNF-and CD40-induced NFKB1 activity at the level of the IKK complex, by inhibiting NFKBIA degradation induced by TNF. When associated with PYCARD, activates CASP1, leading to the secretion of mature proinflammatory cytokine IL1B. May be a component of the inflammasome, a protein complex which also includes PYCARD, CARD8 and CASP1 and whose function would be the activation of proinflammatory caspases.
Synonyms
NACHT, LRR and PYD domains-containing protein 2|Nucleotide-binding site protein 1|PYRIN domain and NACHT domain-containing protein 1|PYRIN-containing APAF1-like protein 2|NLRP2|NALP2|NBS1|PAN1|PYPAF2
Gene ID
55655
UniProt
Q9NX02
Host
Rabbit
Reactivity
Human, Mouse
Immunogen
NLR family, pyrin domain containing 2
Target
NLRP2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Immunology
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IHC: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
105-110 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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