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NKIRAS2 antibody

CAT: 0710-FNab05746Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05746Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Atypical Ras-like protein that acts as a potent regulator of NF-kappa-B activity by preventing the degradation of NF-kappa-B inhibitor beta (NFKBIB) by most signals, explaining why NFKBIB is more resistant to degradation. May act by blocking phosphorylation of NFKBIB and nuclear localization of p65/RELA NF-kappa-B subunit. It is unclear whether it acts as a GTPase. Both GTP-and GDP-bound forms block phosphorylation of NFKBIB (By similarity) .
Synonyms
NF-kappa-B inhibitor-interacting Ras-like protein 2|I-kappa-B-interacting Ras-like protein 2 (Kappa B-Ras protein 2, KappaB-Ras2) |NKIRAS2|KBRAS2
Gene ID
28511
UniProt
Q9NYR9
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
NFKB inhibitor interacting Ras-like 2
Target
NKIRAS2
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF
Field of Research
Signal Transduction
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
22 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF

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