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NFIL3 antibody

CAT: 0710-FNab05700Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05700Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Acts as a transcriptional regulator that recognizes and binds to the sequence 5'-[GA]TTA[CT]GTAA[CT]-3', a sequence present in many cellular and viral promoters. Represses transcription from promoters with activating transcription factor (ATF) sites. Represses promoter activity in osteoblasts (By similarity) . Represses transcriptional activity of PER1 (By similarity) . Represses transcriptional activity of PER2 via the B-site on the promoter (By similarity) . Activates transcription from the interleukin-3 promoter in T-cells. Competes for the same consensus-binding site with PAR DNA-binding factors (DBP, HLF and TEF) (By similarity) . Component of the circadian clock that acts as a negative regulator for the circadian expression of PER2 oscillation in the cell-autonomous core clock (By similarity) . Protects pro-B cells from programmed cell death (By similarity) .
Synonyms
Nuclear factor interleukin-3-regulated protein|E4 promoter-binding protein 4|Interleukin-3 promoter transcriptional activator|Interleukin-3-binding protein 1|Transcriptional activator NF-IL3A|NFIL3|E4BP4|IL3BP1
Gene ID
4783
UniProt
Q16649
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Nuclear factor, interleukin 3 regulated
Target
NFIL3
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IP
Field of Research
Neuroscience, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
55-60 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IP

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