NEDD4 antibody

NEDD4 antibody

• Background: This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
• Synonyms: E3 ubiquitin-protein ligase NEDD4|Cell proliferation-inducing gene 53 protein|HECT-type E3 ubiquitin transferase NEDD4|Neural precursor cell expressed developmentally down-regulated protein 4 (NEDD-4)|NEDD4|KIAA0093|NEDD4-1|RPF1
• CAS Number: 9007-83-4
• Gene ID: 4734
• UniProt: P46934
• Host: Rabbit
• Reactivity: Human
• Immunogen: neural precursor cell expressed, developmentally down-regulated 4
• Target: NEDD4
• Clonality: Polyclonal
• Isotype: IgG
• Applications: ELISA, WB, IHC
• Field of Research: Epigenetics, Metabolism
• Purification: Immunogen affinity purified
• Dilution: WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
• Purity: ≥95% as determined by SDS-PAGE
• Form: Liquid
• Molecular Weight: 120 kDa
• Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)