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NEDD4 antibody

CAT: 0710-FNab05645Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05645Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.
Synonyms
E3 ubiquitin-protein ligase NEDD4|Cell proliferation-inducing gene 53 protein|HECT-type E3 ubiquitin transferase NEDD4|Neural precursor cell expressed developmentally down-regulated protein 4 (NEDD-4) |NEDD4|KIAA0093|NEDD4-1|RPF1
Gene ID
4734
UniProt
P46934
Host
Rabbit
Reactivity
Human
Immunogen
Neural precursor cell expressed, developmentally down-regulated 4
Target
NEDD4
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IHC
Field of Research
Epigenetics, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000; IHC: 1:50 - 1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
120 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IHC

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