NEDD4 antibody

• Background:

  This gene is the founding member of the NEDD4 family of HECT ubiquitin ligases that function in the ubiquitin proteasome system of protein degradation. The encoded protein contains an N-terminal calcium and phospholipid binding C2 domain followed by multiple tryptophan-rich WW domains and, a C-terminal HECT ubiquitin ligase catalytic domain. It plays critical role in the regulation of a number of membrane receptors, endocytic machinery components and the tumor suppressor PTEN.

• Synonyms:

  E3 ubiquitin-protein ligase NEDD4|Cell proliferation-inducing gene 53 protein|HECT-type E3 ubiquitin transferase NEDD4|Neural precursor cell expressed developmentally down-regulated protein 4 (NEDD-4) |NEDD4|KIAA0093|NEDD4-1|RPF1

• Gene ID:

  4734

• UniProt:

  P46934

• Host:

  Rabbit

• Reactivity:

  Human

• Immunogen:

  Neural precursor cell expressed, developmentally down-regulated 4

• Target:

  NEDD4

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Epigenetics, Metabolism

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  120 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC