NCOR2 antibody

• Background :

  Transcriptional corepressor. Mediates the transcriptional repression activity of some nuclear receptors by promoting chromatin condensation, thus preventing access of the basal transcription. Isoform 1 and isoform 5 have different affinities for different nuclear receptors. Involved in the regulation BCL6-dependent of the germinal center (GC) reactions, mainly through the control of the GC B-cells proliferation and survival.

• Synonyms :

  Nuclear receptor corepressor 2 (N-CoR2) |CTG repeat protein 26|SMAP270|Silencing mediator of retinoic acid and thyroid hormone receptor (SMRT) |T3 receptor-associating factor (TRAC) |Thyroid-, retinoic-acid-receptor-associated corepressor|NCOR2|CTG26

• Gene ID :

  9612

• UniProt :

  Q9Y618

• Host :

  Rabbit

• Reactivity :

  Human

• Immunogen :

  Nuclear receptor co-repressor 2

• Target :

  NCOR2

• Clonality :

  Polyclonal

• Isotype :

  IgG

• Applications :

  ELISA, WB, IF

• Field of Research :

  Metabolism

• Purification :

  Immunogen affinity purified

• Dilution :

  WB: 1:500 - 1:2000; IF: 1:50 - 1:100

• Purity :

  ≥95% as determined by SDS-PAGE

• Form :

  Liquid

• Molecular Weight :

  180 kDa, 275 kDa

• Shipping Conditions :

  4°C with ice bag

• Storage Conditions :

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications :

  ELISA, WB, IF