NCKIPSD antibody

• Background:

  Has an important role in stress fiber formation induced by active diaphanous protein homolog 1 (DRF1) . Induces microspike formation, in vivo (By similarity) . In vitro, stimulates N-WASP-induced ARP2/3 complex activation in the absence of CDC42 (By similarity) . May play an important role in the maintenance of sarcomeres and/or in the assembly of myofibrils into sarcomeres. Implicated in regulation of actin polymerization and cell adhesion. Plays a role in angiogenesis.

• Synonyms:

  NCK-interacting protein with SH3 domain|54 kDa VacA-interacting protein|54 kDa vimentin-interacting protein (VIP54) |90 kDa SH3 protein interacting with Nck|AF3p21|Dia-interacting protein 1 (DIP-1) |Diaphanous protein-interacting protein|SH3 adapter protein SPIN90|WASP-interacting SH3-domain protein (WISH) |Wiskott-Aldrich syndrome protein-interacting protein|NCKIPSD|AF3P21|SPIN90

• Gene ID:

  51517

• UniProt:

  Q9NZQ3

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  NCK interacting protein with SH3 domain

• Target:

  NCKIPSD

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC, IP

• Field of Research:

  Signal Transduction

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500-1:2000; IP: 1:200-1:1000; IHC: 1:20-1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  80 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC, IP