NCK2 antibody

• Background:

  This gene encodes a member of the NCK family of adaptor proteins. The protein contains three SH3 domains and one SH2 domain. The protein has no known catalytic function but has been shown to bind and recruit various proteins involved in the regulation of receptor protein tyrosine kinases. It is through these regulatory activities that this protein is believed to be involved in cytoskeletal reorganization. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

• Synonyms:

  Cytoplasmic protein NCK2|Growth factor receptor-bound protein 4|NCK adaptor protein 2 (Nck-2) |SH2/SH3 adaptor protein NCK-beta|NCK2|GRB4

• Gene ID:

  8440

• UniProt:

  O43639

• Host:

  Rabbit

• Reactivity:

  Human, Mouse, Rat

• Immunogen:

  NCK adaptor protein 2

• Target:

  NCK2

• Clonality:

  Polyclonal

• Isotype:

  IgG

• Applications:

  ELISA, WB, IHC

• Field of Research:

  Signal Transduction, Developmental biology

• Purification:

  Immunogen affinity purified

• Dilution:

  WB: 1:500 - 1:2000; IHC: 1:50 - 1:200

• Purity:

  ≥95% as determined by SDS-PAGE

• Form:

  Liquid

• Molecular Weight:

  43 kDa

• Shipping Conditions:

  4°C with ice bag

• Storage Conditions:

  PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

• Tested Applications:

  ELISA, WB, IHC