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MPPE1 antibody

CAT: 0710-FNab05293Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05293Size:100 µg
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Background
Metallophosphoesterase required for transport of GPI-anchor proteins from the endoplasmic reticulum to the Golgi. Acts in lipid remodeling steps of GPI-anchor maturation by mediating the removal of a side-chain ethanolamine-phosphate (EtNP) from the second Man (Man2) of the GPI intermediate, an essential step for efficient transport of GPI-anchor proteins.
Synonyms
Metallophosphoesterase 1|Post-GPI attachment to proteins factor 5|MPPE1|PGAP5
Gene ID
65258
UniProt
Q53F39
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Metallophosphoesterase 1
Target
MPPE1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
45 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

UniProtKB · Q53F39

Metallophosphoesterase 1

MPPE1_HUMAN · Homo sapiens

View on UniProt ↗
Primary accession
Q53F39
Review status
UniProtKB reviewed (Swiss-Prot)
Gene
MPPE1
Protein existence
1: Evidence at protein level
Organism
Homo sapiens (Human)
Taxonomy ID
9606
Alternative names
—
EC number
3.1.-.-
Processing
—
Secondary accessions
B0YJ39, B0YJ40, B0YJ41, B5ME53, B7WNJ3, D3DUI5, D3DUI7, Q6GMP1, Q8TAD6, Q8TE26, Q8WZ32, Q9BU58, Q9H958, Q9HAI4
Protein keywords

Coding sequence diversity

Alternative splicing

Biological process

ER-Golgi transportGPI-anchor biosynthesisTransport

Molecular function

Hydrolase

Ligand

ManganeseMetal-binding

Cellular component

Membrane

Technical term

Proteomics identificationReference proteome

Domain

TransmembraneTransmembrane helix

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