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MNAT1 antibody

CAT: 0710-FNab05252Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05252Size:100 µg
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24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Stabilizes the cyclin H-CDK7 complex to form a functional CDK-activating kinase (CAK) enzymatic complex. CAK activates the cyclin-associated kinases CDK1, CDK2, CDK4 and CDK6 by threonine phosphorylation. CAK complexed to the core-TFIIH basal transcription factor activates RNA polymerase II by serine phosphorylation of the repetitive C-terminal domain (CTD) of its large subunit (POLR2A), allowing its escape from the promoter and elongation of the transcripts. Involved in cell cycle control and in RNA transcription by RNA polymerase II.
Synonyms
CDK-activating kinase assembly factor MAT1|CDK7/cyclin-H assembly factor|Cyclin-G1-interacting protein|Menage a trois|RING finger protein 66|RING finger protein MAT1|p35|p36|MNAT1|CAP35|MAT1|RNF66
Gene ID
4331
UniProt
P51948
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Menage a trois homolog 1, cyclin H assembly factor (Xenopus laevis)
Target
MNAT1
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB, IF, IP
Field of Research
Cell Division and Proliferation, Metabolism
Purification
Immunogen affinity purified
Dilution
WB: 1:500-1:2000; IP: 1:200-1:1000; IF: 1:20-1:200
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
36 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB, IF, IP

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