MEF2A antibody
CAT:
710-FNab05100
Size:
100 µg
Price:
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- Availability: 24/48H Stock Items & 2 to 6 Weeks non Stock Items.
- Dry Ice Shipment: No
MEF2A antibody
- Background: Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT](4)TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
- Synonyms: Myocyte-specific enhancer factor 2A|Serum response factor-like protein 1|MEF2A|MEF2
- CAS Number: 9007-83-4
- Gene ID: 4205
- UniProt: Q02078
- Host: Rabbit
- Reactivity: Human, Mouse, Rat
- Immunogen: myocyte enhancer factor 2A
- Target: MEF2A
- Clonality: Polyclonal
- Isotype: IgG
- Applications: ELISA, WB
- Field of Research: Neuroscience, Cardiovascular, Metabolism, Developmental biology
- Purification: Immunogen affinity purified
- Dilution: WB: 1:500 - 1:2000
- Purity: ≥95% as determined by SDS-PAGE
- Form: Liquid
- Molecular Weight: 54 kDa
- Storage Conditions: PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months(Avoid repeated freeze / thaw cycles.)