MEF2A antibody

CAT: 0710-FNab05100Size: 100 µgDry Ice: NoHazardous: No
CAT#:0710-FNab05100Size:100 µg
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AVAILABILITY: InStock
24/48H Stock Items & 2 to 6 Weeks non Stock Items.
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Background
Transcriptional activator which binds specifically to the MEF2 element, 5'-YTA[AT] (4) TAR-3', found in numerous muscle-specific genes. Also involved in the activation of numerous growth factor-and stress-induced genes. Mediates cellular functions not only in skeletal and cardiac muscle development, but also in neuronal differentiation and survival. Plays diverse roles in the control of cell growth, survival and apoptosis via p38 MAPK signaling in muscle-specific and/or growth factor-related transcription. In cerebellar granule neurons, phosphorylated and sumoylated MEF2A represses transcription of NUR77 promoting synaptic differentiation. Associates with chromatin to the ZNF16 promoter.
Synonyms
Myocyte-specific enhancer factor 2A|Serum response factor-like protein 1|MEF2A|MEF2
Gene ID
4205
UniProt
Q02078
Host
Rabbit
Reactivity
Human, Mouse, Rat
Immunogen
Myocyte enhancer factor 2A
Target
MEF2A
Clonality
Polyclonal
Isotype
IgG
Applications
ELISA, WB
Field of Research
Neuroscience, Cardiovascular, Metabolism, Developmental biology
Purification
Immunogen affinity purified
Dilution
WB: 1:500 - 1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
54 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Tested Applications
ELISA, WB

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