MED28 antibody

CAT: 0710-FNab05094Size: 100 µgDry Ice: NoHazardous: No

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CAT#:0710-FNab05094Size:100 µg

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24/48H Stock Items & 2 to 6 Weeks non Stock Items.

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Background

Component of the Mediator complex, a coactivator involved in the regulated transcription of nearly all RNA polymerase II-dependent genes. Mediator functions as a bridge to convey information from gene-specific regulatory proteins to the basal RNA polymerase II transcription machinery. Mediator is recruited to promoters by direct interactions with regulatory proteins and serves as a scaffold for the assembly of a functional preinitiation complex with RNA polymerase II and the general transcription factors. May be part of a complex containing NF2/merlin that participates in cellular signaling to the actin cytoskeleton downstream of tyrosine kinase signaling pathways.

Synonyms

Gene ID

80306

UniProt

Q9H204

Host

Rabbit

Reactivity

Human, Mouse, Rat

Immunogen

Mediator complex subunit 28

Target

MED28

Clonality

Polyclonal

Isotype

IgG

Applications

ELISA, WB

Field of Research

Cancer, Metabolism

Purification

Immunogen affinity purified

Dilution

IHC: 1:20-1:200

Purity

≥95% as determined by SDS-PAGE

Form

Liquid

Molecular Weight

25-28 kDa

Shipping Conditions

4°C with ice bag

Storage Conditions

PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)

Tested Applications

ELISA, WB

UniProtKB · Q9H204

Mediator of RNA polymerase II transcription subunit 28

MED28_HUMAN · Homo sapiens

View on UniProt ↗

Primary accession: Q9H204
Review status: UniProtKB reviewed (Swiss-Prot)
Gene: MED28
Protein existence: 1: Evidence at protein level
Organism: Homo sapiens (Human)
Taxonomy ID: 9606
Alternative names: —
EC number: —
Processing: —
Secondary accessions: Q9BZJ5

Protein keywords

Technical term

3D-structureProteomics identificationReference proteome

Molecular function

Actin-bindingActivator

Domain

Coiled coil

Cellular component

CytoplasmMembraneNucleus

Biological process

TranscriptionTranscription regulation

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Alternative Products

Catalog	Name
4731-01	MED28 Antibody