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MCM2 antibody

CAT: 0710-FNab05057Size: 100 µgDry Ice: NoHazardous: No
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CAT#:0710-FNab05057Size:100 µg
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Background
Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division.
Synonyms
DNA replication licensing factor MCM2|Minichromosome maintenance protein 2 homolog|Nuclear protein BM28|MCM2|BM28|CCNL1|CDCL1|KIAA0030
Gene ID
4171
UniProt
P49736
Host
Mouse
Reactivity
Human
Immunogen
Minichromosome maintenance complex component 2
Target
MCM2
Clonality
Monoclonal
Isotype
IgG2a
Applications
ELISA, WB
Field of Research
Epigenetics, Cancer, Immunology, Metabolism
Purification
Protein A+G purification
Dilution
WB: 1:1000-1:2000
Purity
≥95% as determined by SDS-PAGE
Form
Liquid
Molecular Weight
116-125 kDa
Shipping Conditions
4°C with ice bag
Storage Conditions
PBS with 0.02% sodium azide and 50% glycerol pH 7.3, -20°C for 12 months (Avoid repeated freeze / thaw cycles.)
Clone ID
4E3
Tested Applications
ELISA, WB

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